Kidney Diseases in Dogs: A Guide to Dog Kidney Problems

Written by: Karuna Subbiah

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Time to read 10 min

Welcome, dog lovers! Ever wondered about your furry friend's kidneys? Well, you're in the right place! This guide discusses common kidney problems in dogs, including kidney failure.

It provides simple and straightforward information without using complicated words. 


Our goal? To help you spot the symptoms of kidney problems in dogs early, understand what might be going on, and keep your pup's kidneys happy and healthy. 


In this comprehensive guide, we'll explore various kidney problems that dogs may encounter, including their symptoms and causes. 


Understanding these conditions and consulting a vet can aid in early detection and proactive management, contributing to the improved quality of life for your furry friend.


Now, let's embark on a tail-wagging journey through the world of doggy kidneys.

1. Chronic Kidney Disease (CKD) in Dogs

Chronic Kidney Disease (CKD) in Dogs

Chronic Kidney Disease is when the kidneys stop working properly, causing long-term kidney failure in dogs. The aging process is often associated with it, although it can affect dogs of any age. CKD necessitates vigilant management and early detection to optimize the quality of life for our furry friends.

Symptoms:

Detecting the symptoms of CKD is pivotal for timely intervention. Keep a watchful eye for:


  • Increased Thirst and Urination: Dogs may exhibit a heightened need for water and frequent urination.
  • Changes in Appetite: A decline in appetite, often leading to weight loss.
  • Lethargy: A general decrease in activity and energy levels.
  • Gastrointestinal Issues: Vomiting and diarrhea may occur.
  • Unpleasant Breath Odor: Caused by the buildup of toxins in the body.

Causes:

Various factors can trigger CKD, including:

  • Aging: Advanced age is a significant risk factor for kidney issues in dogs.
  • Diet and Lifestyle: Too much protein intake and sedentary lifestyle. 
  • Underlying Health Conditions: Certain health issues, such as high blood pressure or frequent urinary tract infections, can lead to CKD.
  • Genetics: Certain breeds may have a genetic predisposition to kidney problems.

2. Acute Kidney Injury (AKI) in Dogs

Acute Kidney Injury (AKI) in Dogs

Acute Kidney Injury is a sudden drop in kidney function that needs immediate attention to prevent acute renal failure in dogs. It can manifest at any age and is often linked to diverse factors such as toxins, infections, or dehydration. 

Symptoms:

Recognition of AKI symptoms is crucial for early detection. Look out for:


  • Sudden Decrease in Urine Production: A noticeable reduction in the volume of urine.
  • Vomiting and Diarrhea: Gastrointestinal disturbances may accompany AKI.
  • Lethargy and Weakness: A sudden decline in overall energy levels.
  • Dehydration Signs: Sunken eyes, dry gums, and increased thirst.

Causes:

Various factors can trigger AKI, including:


  • Toxins: Ingestion of substances harmful to the kidneys, such as certain plants or medications.
  • Infections: Bacterial infections affecting the kidneys, often stemming from untreated urinary tract infections.
  • Dehydration: Insufficient fluid intake leads to a compromised renal function.

3. Dog Renal Dysplasia

Dog Renal Dysplasia

Renal Dysplasia is a congenital condition characterized by abnormal kidney development. Unlike other kidney problems, this issue is present from birth and can lead to long-term complications.

Symptoms:

Identification of Renal Dysplasia symptoms is essential for timely intervention. Keep an eye out for:


  • Excessive Drinking and Urination: An early indicator of potential kidney issues.
  • Poor Growth and Development: Failure to thrive or stunted growth in young dogs.
  • Frequent Urinary Tract Infections: Renal Dysplasia can predispose dogs to recurring infections.

Causes:

Genetic factors primarily trigger Renal Dysplasia.


  • Genetic Predisposition: Certain breeds may have a higher likelihood of carrying the genes associated with Renal Dysplasia.
  • Inherited Mutations: Genetic abnormalities affecting normal kidney development.

4. Glomerulonephritis in Dogs

Glomerulonephritis in Dogs

Glomerulonephritis is an inflammatory condition that primarily affects the glomeruli, the tiny blood vessels responsible for filtering waste products in the kidneys, impacting the essential blood flow to the kidneys. Understanding the intricacies of Glomerulonephritis is crucial for pet owners, as it can lead to long-term kidney issues.

Symptoms:

Recognition of Glomerulonephritis symptoms is key for early intervention. Look out for:


  • Increased Urination: Dogs may experience an uptick in urination.
  • Fluid Retention: Swelling, particularly around the face and limbs.
  • Changes in Urine Color: Blood in the urine or a dark color may be evident.
  • High Blood Pressure: Glomerulonephritis can contribute to hypertension.

Causes:

Various factors can trigger Glomerulonephritis, including:


  • Infections: Bacterial or viral infections affecting the kidneys.
  • Toxins: Exposure to certain toxins or medications. 
  • Immune System Disorders: Conditions where the immune system mistakenly attacks the glomeruli. 

5. Pyelonephritis in Dogs

 Pyelonephritis in Dogs

Pyelonephritis is a bacterial infection that targets the kidneys, often stemming from untreated urinary tract infections. 

Symptoms:

Recognition of Pyelonephritis symptoms is pivotal for swift intervention. Look out for:


  • Increased Urination: Dogs may exhibit frequent urination.
  • Discomfort or Pain During Urination: Vocal sounds or signs of discomfort while urinating.
  • Fever: Elevated body temperature may accompany the infection.
  • Lethargy and Weakness: A decrease in overall energy levels.

Causes:

Bacterial invasion, often originating from the urinary tract, primarily triggers Pyelonephritis.


  • Urinary Tract Infections (UTIs): Untreated UTIs can ascend to the kidneys.
  • Bladder Stones: Stones in the bladder can create a conducive environment for bacterial growth.
  • Anatomical Abnormalities: Structural issues in the urinary tract can contribute to infections.

6. Nephrolithiasis (Dog Kidney Stones)

 Nephrolithiasis (Dog Kidney Stones)

Nephrolithiasis refers to the formation of mineral or crystal masses within the kidneys, hindering the normal filtration process. 

Symptoms:

Recognition of Nephrolithiasis symptoms is key for early intervention. Look out for:


  • Pain or Discomfort During Urination: Dogs may exhibit signs of distress while urinating.
  • Frequent Urination: Increased trips to relieve themselves.
  • Blood in Urine: Hematuria, visible as discolored or bloody urine.
  • Lethargy and Decreased Appetite: Discomfort may lead to changes in behavior and eating habits.

Causes:

Various factors can trigger Nephrolithiasis, including:


  • Dietary Factors: Imbalances in mineral intake or certain diets may contribute.
  • Dehydration: Insufficient water intake can lead to concentrated urine, making stone formation.
  • Breed Predisposition: Certain breeds have a higher vulnerability to kidney stone formation.

7. Hydronephrosis in Dogs

Hydronephrosis in Dogs

Hydronephrosis refers to the abnormal collection of urine within the kidneys, leading to swelling and potential damage.

Symptoms:

Recognition of Hydronephrosis symptoms is pivotal for early intervention. Look out for:


  • Abdominal Discomfort or Swelling: Kidney swelling leads to enlargement of the abdomen.
  • Changes in Urination Patterns: Dogs may exhibit altered urination behaviors.
  • Lethargy and Decreased Appetite: General signs of discomfort and potential kidney dysfunction.

Causes:

Various factors can trigger Hydronephrosis, including:


  • Urinary Tract Obstruction: Blockages in the urinary tract preventing the normal flow of urine.
  • Congenital Anomalies: Structural abnormalities present from birth affecting urine drainage.
  • Infections or Stones: Conditions that hinder the proper passage of urine.

8. Polycystic Kidney Disease (PKD) in Dogs

Polycystic Kidney Disease (PKD) in Dogs

Polycystic Kidney Disease causes fluid-filled cysts in the kidneys, which disrupt their normal structure and function.

Symptoms:

Recognition of PKD symptoms is key for early intervention. Look out for:


  • Abdominal Enlargement: Presence of multiple cysts results in swelling.
  • Increased Urination: Frequent urination or changes in urinary habits.
  • High Blood Pressure: PKD can contribute to hypertension.
  • Lethargy and Decreased Appetite: Signs of discomfort and potential kidney dysfunction.

Causes:

Genetic factors primarily trigger PKD like:


  • Inherited Mutations: Genetic abnormalities affecting the normal development of the kidneys.
  • Breed Predisposition: Certain breeds may have a higher likelihood of carrying the genes associated with PKD.

9. Amyloidosis in Dogs

Amyloidosis in Dogs

Amyloidosis involves the collection of abnormal protein deposits called amyloids in organs and tissues. When these deposits affect the kidneys, it can lead to impaired function and potential complications.

Symptoms:

Recognition of Amyloidosis symptoms is pivotal for early intervention. Look out for:


  • Changes in Urination Patterns: Altered frequency or appearance of urine.
  • Swelling: Fluid retention results in swelling particularly around the limbs and face.
  • Weight Loss: Unexplained loss of body weight.
  • Loss of Appetite and Lethargy: Signs of discomfort and systemic involvement.

Causes:

Various factors can trigger Amyloidosis, including:


  • Genetic Factors: Certain breeds may have a higher predisposition.
  • Chronic Inflammation: Ongoing inflammatory conditions can contribute.
  • Unknown Causes: In some cases, the exact cause may remain unclear.

10. Toxic Nephropathy in Dogs

Toxic Nephropathy in Dogs

Toxic Nephropathy refers to kidney damage caused by the ingestion or exposure to toxins.

Symptoms:

Recognition of Toxic Nephropathy symptoms is pivotal for early intervention. Look out for:


  • Decreased Urination: A reduction in the frequency or volume of urine.
  • Vomiting and Diarrhea: Gastrointestinal disturbances may accompany toxic exposure.
  • Lethargy and Weakness: General signs of discomfort and potential kidney dysfunction.
  • Dehydration: Sunken eyes, dry gums, and increased thirst.

Causes:

Various substances Toxic Nephropathy, including:


  • Certain Medications: Overdosing or adverse reactions to medications.
  • Plants and Foods: Ingestion of toxic plants or foods harmful to the kidneys.
  • Chemicals and Poisons: Exposure to household chemicals, pesticides, or poisonous substances.

11. Dehydration-Related Kidney Problems in Dogs

Dehydration-Related Kidney Problems in Dogs

Dehydration can pose a direct threat to kidney health, potentially leading to various complications. 

Symptoms:

Recognition of Dehydration-Related Kidney Problem symptoms is pivotal for early intervention. Look out for:


  • Decreased Urination: A noticeable reduction in the frequency or volume of urine.
  • Sunken Eyes: A sign of dehydration affecting overall body fluid levels.
  • Lethargy and Weakness: General signs of discomfort and potential kidney dysfunction.
  • Dry Gums and Skin: Indicators of insufficient hydration.

Causes:

Various factors trigger Dehydration-Related Kidney Problems, including:


  • Inadequate Water Intake: Insufficient access to water, especially in hot weather.
  • Illnesses: Conditions like vomiting or diarrhea leading to fluid loss.
  • Excessive Exercise or Heat Exposure: Intense physical activity or high temperatures contribute to dehydration.

12. Hypertension (Dog High Blood Pressure)

Hypertension (Dog High Blood Pressure)

Hypertension or high BP in dogs emerges as a silent threat, with far-reaching consequences on various organs, including the kidneys. High blood pressure can significantly affect the cardiovascular system and, notably, the delicate filtration units within the kidneys. 

Symptoms:

Recognition of Hypertension symptoms is pivotal for early intervention. Look out for:


  • Increased Thirst and Urination: Increased thirst and urination make up for reactions to high blood pressure.
  • Vision Issues: Changes in behavior or apparent difficulty seeing.
  • Disorientation or Seizures: Advanced cases may lead to neurological symptoms.
  • Lethargy and Weakness: Signs of potential organ damage, including the kidneys.

Causes:

Various factors can trigger hypertension in dogs, including:


  • Underlying Conditions: Kidney disease, hormonal imbalances, or heart problems.
  • Age and Breed Predisposition: Older dogs and certain breeds may be more susceptible.
  • Obesity: Excessive weight can contribute to hypertension.

13. Autoimmune Kidney Diseases in Dogs

Autoimmune Kidney Diseases in Dogs

Autoimmune Kidney Diseases involve the immune system mistakenly targeting and damaging the kidneys, disrupting their normal function. 

Symptoms:

Recognition of Autoimmune Kidney Disease symptoms is pivotal for early intervention. Look out for:


  • Changes in Urination Patterns: Altered frequency or appearance of urine.
  • Swelling: Particularly around the limbs and face because of fluid retention.
  • Blood in Urine: Hematuria, visible as discolored or bloody urine.
  • Lethargy and Decreased Appetite: Signs of discomfort and potential kidney dysfunction.

Causes:

Various factors can trigger Autoimmune Kidney Diseases, including:


  • Genetic Predisposition: Certain breeds may have a higher likelihood of autoimmune conditions.
  • Infections: Chronic infections can sometimes trigger an autoimmune response.
  • Unknown Causes: In some cases, the exact cause may remain unclear.

14. Dog Leptospirosis

Dog Leptospirosis

Leptospirosis emerges as a zoonotic bacterial infection with potential kidney involvement. Leptospirosis is caused by bacteria of the genus Leptospira, and it can affect various organs, including the kidneys. 

Symptoms:

Recognition of Leptospirosis symptoms is pivotal for early intervention. Look out for:


  • Fever: Elevated body temperature is a common early sign.
  • Muscle Pain and Stiffness: Dogs may exhibit signs of discomfort.
  • Vomiting and Diarrhea: Gastrointestinal disturbances are common.
  • Lethargy and Decreased Appetite: General signs of illness.

Causes:

Leptospirosis is primarily caused by exposure to contaminated water or soil, and it can be triggered by various factors, including:


  • Direct Contact with Infected Urine: Through wounds or mucous membranes. 
  • Contaminated Environments: Stagnant water or moist soil can harbor the bacteria.
  • Contact with Infected Animals: Urine from infected animals is a common source. 

15. Lyme Disease in Dogs

Lyme Disease in Dogs

Lyme Disease is caused by the bacterium Borrelia burgdorferi, transmitted through the bite of infected ticks. While primarily known for its effects on joints, Lyme Disease can also impact the kidneys.

Symptoms:

Recognition of Lyme Disease symptoms is pivotal for early intervention. Look out for:


  • Lameness or Joint Pain: A hallmark sign, often shifting from one leg to another.
  • Fever: Elevated body temperature is common.
  • Lethargy and Decreased Appetite: General signs of illness.
  • Swollen Lymph Nodes: Enlarged lymph nodes may be palpable.

Causes:

Caused because of the bite of infected black-legged ticks, including:


  • Tick Exposure: Particularly in wooded or grassy areas.
  • Incomplete Tick Removal: Leaving a tick attached for an extended period increases the risk.
  • Geographic Prevalence: Regions with high tick populations pose an increased risk.

Conclusion

This comprehensive guide aims to empower pet owners with knowledge about various kidney problems that can affect dogs. 


Early recognition of symptoms and understanding of potential causes are crucial for prompt veterinary intervention.

 

If your dog has signs of kidney problems, take them to a vet. The vet will give them a check-up and create a treatment plan specifically for their condition.


Remember, proactive care and regular veterinary check-ups are essential for maintaining your dog's kidney health. Stay informed, and ensure your furry friend leads a happy and healthy life.


Armed with this pup-tastic knowledge, you're now the kidney superhero your furball deserves. Keep those tails wagging, and here's to a kidney-full life for your four-legged amigo!


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