If you’re a dog parent, keeping your furry friend safe from parasites is probably high on your priority list. That’s where Ivermectin comes in. It’s an anti-parasitic medication often used to prevent heartworm and other parasitic infections in pets. Ivermectin doesn’t just target heartworms, though—it can help protect against a variety of parasites like roundworms, mites, and more.

How Does Ivermectin Work?

Ivermectin is a broad-spectrum anti-parasitic medication that works by targeting the nervous system of parasites. It interferes with the transmission of nerve signals in these organisms, causing paralysis and eventual death. Here’s a breakdown of how it works:

1. Nerve Signal Disruption: Ivermectin binds to certain receptors in the parasite’s nervous system, specifically glutamate-gated chloride channels. This causes an influx of chloride ions into the cells, which disrupts normal nerve signaling.

2. Paralysis and Death: Without the ability to transmit nerve signals, the parasite becomes paralyzed. This paralysis means the parasite can no longer feed, reproduce, or maintain basic functions, leading to its death.

3. Elimination from the Body: Once the parasites are incapacitated, the dog’s immune system and bodily processes eliminate them. In some cases, the dead parasites are expelled naturally through feces or reabsorbed and broken down by the dog’s body.

Ivermectin is particularly effective against internal parasites like heartworms, roundworms, and external parasites like mites and lice. This mechanism ensures that parasites are stopped before they cause serious damage to your dog’s health.

How Is Ivermectin Administered?

Ivermectin can be administered in several forms, depending on the condition being treated and your dog’s health. It’s available in:

1. Oral Tablets or Liquids: The most common form, oral Ivermectin is easy to administer at home. It’s often used for heartworm prevention and some intestinal parasites. The tablet or liquid is ingested, where it is absorbed into the bloodstream to target parasites.

2. Topical Solutions: These are typically used for external parasites like mites or lice. The solution is applied directly to your dog’s skin and absorbed through the skin layers. It spreads systemically to reach the targeted parasites.

3. Injectable Form: Veterinarians often prefer administering Ivermectin through an injection, especially when long-term protection is needed. The injectable form delivers the medication directly into your dog’s bloodstream for immediate absorption, making it effective faster than oral or topical methods. This method is common in high-risk areas where parasites are prevalent.

In all cases, it’s essential to follow your vet’s instructions carefully. Overdosing or improper administration can lead to serious side effects. If your dog receives Ivermectin regularly, your vet will prescribe a dose based on their weight and health status.

What If You Miss a Dose?

Life gets busy, and sometimes, you may forget to administer a dose of your pet’s Ivermectin or your shipment could be delayed. If this happens, don’t panic! The best thing to do is reach out to your vet. They can advise you on how to proceed. Missing a dose may leave your pet vulnerable to parasites, so it’s important to get back on track as soon as possible.

Potential Side Effects of Ivermectin

While Ivermectin is generally safe for dogs when used correctly, there are potential side effects, especially if dosed improperly. Common side effects include:

1. Digestive Issues: Some dogs may experience vomiting, diarrhea, or loss of appetite shortly after taking Ivermectin. These side effects are usually mild and resolve on their own. However, if they persist for more than a day, you should consult your vet.

2. Lethargy or Weakness: Ivermectin can sometimes cause a drop in energy levels, making your dog appear more tired or lethargic than usual. This usually subsides as the medication is processed by their body.

3. Neurological Symptoms (In High Doses): In cases of overdose or when administered to sensitive breeds, Ivermectin can cause more severe symptoms like tremors, confusion, dilated pupils, and seizures. This happens when the drug crosses the blood-brain barrier and affects the dog’s central nervous system.

To reduce the risk of side effects, always adhere to the prescribed dose and closely monitor your dog after administration, especially if it’s their first time receiving the medication.

Breed Sensitivities

Certain dog breeds have a genetic mutation known as MDR1 (Multi-Drug Resistance Gene Mutation), which makes them more sensitive to Ivermectin. These breeds include:

• Collies
• Australian Shepherds
• Shetland Sheepdogs (Shelties)
• Old English Sheepdogs
• Border Collies

Dogs with the MDR1 mutation have a compromised blood-brain barrier, which allows Ivermectin to reach the brain and potentially cause neurological toxicity. Symptoms of Ivermectin toxicity in sensitive breeds include severe lethargy, tremors, seizures, and even coma.

For dogs in these breeds, vets will either avoid prescribing Ivermectin altogether or adjust the dosage carefully. Genetic testing is available to determine if your dog carries the MDR1 gene mutation, and it’s advisable to discuss this with your vet if you own one of these breeds.

Drug Interactions

It’s essential to inform your vet about any other medications your dog is taking. Some drugs can interact with Ivermectin, potentially causing harmful effects. This includes certain antibiotics, antifungals, and even heart medications. Your vet will guide you on how to proceed safely if your dog needs Ivermectin alongside other treatments.

Monitoring Your Dog During Treatment

While most dogs tolerate Ivermectin well, it’s crucial to monitor them during the course of treatment, particularly if they are on high doses or have an underlying health condition. Here’s what you should do:

1. Watch for Side Effects: After administering Ivermectin, keep an eye on your dog for any immediate signs of distress like vomiting, tremors, or unusual behavior. If these occur, contact your vet immediately.

2. Regular Vet Visits: If your dog is on long-term Ivermectin, such as for heartworm prevention, regular vet check-ups are recommended. These visits allow your vet to monitor for any adverse reactions and ensure that the medication is working as expected.

3. Blood Tests: In cases of prolonged use, your vet may recommend periodic blood tests to check liver and kidney function, ensuring that the medication is not causing any internal harm.

Routine vet visits during Ivermectin treatment can help catch potential issues early, ensuring your dog stays healthy and parasite-free.

How to Store Ivermectin

Proper storage of Ivermectin is essential to maintain its effectiveness and prevent accidental ingestion by pets or children. Here’s how you should store it:

1. Cool, Dry Place: Keep Ivermectin in a location away from direct sunlight and moisture, as heat and humidity can degrade the medication and reduce its efficacy. A medicine cabinet or drawer in a cool area of your home is ideal.

2. Out of Reach of Pets and Children: Ivermectin, especially in liquid or tablet form, can be dangerous if ingested in large quantities. Always store the medication in a secure location that pets and children cannot access.

 3.Check Expiry Date: Like all medications, Ivermectin has an expiry date. Using expired medication can be ineffective or harmful, so regularly check the label and dispose of any outdated doses properly, following local disposal guidelines.

By following these storage tips, you can ensure the medication remains effective and safe for your dog’s use.

What to Do in Case of Emergency

Accidental overdose or ingestion of Ivermectin can be dangerous. Here’s what to do if you suspect an emergency:

1. Recognize Symptoms of Overdose: Early symptoms of Ivermectin toxicity include drooling, tremors, confusion, uncoordinated movements, and dilated pupils. In severe cases, it can lead to seizures or coma.

2. Contact Your Vet Immediately: If you notice any of these symptoms or suspect your dog has consumed an excessive dose of Ivermectin, call your vet or an emergency animal clinic immediately. Time is crucial in preventing serious harm.

3. Contact Poison Control: For immediate assistance, you can also contact your vet. They can provide step-by-step guidance on what to do next.

4. Provide Information: Be prepared to provide details such as the amount of Ivermectin ingested, your dog’s weight, and any symptoms they’re showing. This information helps the vet or poison control offer the best advice quickly.

Early intervention is key in emergencies, and prompt treatment can significantly improve outcomes.

Is Ivermectin Safe for Your Dog?

In most cases, Ivermectin is considered safe when administered under veterinary guidance. However, as with all medications, being aware of your pet’s unique needs is key to ensuring their health. Always consult with your vet, especially if you’re uncertain about the right dosage or form of the medication. Remember, your pet’s health journey is personal, and the guidance of a trusted veterinarian is invaluable.

FAQs

1. Can Ivermectin be used on pregnant or nursing dogs?

Ivermectin should be used with caution in pregnant or nursing dogs. While it is considered safe at low doses, always consult your veterinarian before administering any medication to ensure the health of both the mother and her puppies.

2. How long does an Ivermectin injection last in dogs?

An Ivermectin injection typically provides protection for about a month, but this can vary based on the dosage and your dog's health. Your vet will recommend the right schedule for your pet.

3. Can puppies receive Ivermectin?

Puppies can be given Ivermectin, but the dosage will be much smaller than for adult dogs. Always follow your vet’s advice when it comes to treating young dogs, as their systems are still developing.

4. Can I buy Ivermectin over the counter?

While you might find Ivermectin available without a prescription in some places, it’s best to use it only under a vet’s guidance. Misuse or incorrect dosages can lead to serious side effects, so always consult with your vet.

5. How can I tell if my dog has a parasite?

Common signs of parasitic infections include diarrhea, weight loss, coughing, and changes in coat condition. If you suspect your dog has parasites, schedule a vet appointment for proper diagnosis and treatment.

Protecting Your Dog’s Health with Ivermectin

Your dog relies on you for their health and well-being, and keeping them safe from parasites is a big part of that. By understanding the role of Ivermectin and consulting with your vet, you’re giving your dog the best chance at a long, happy, and healthy life.

Whether it’s Ivermectin injections, oral medications, or topical treatments, the key is regular prevention. This keeps the parasites at bay and helps your dog stay their energetic, lovable self. From avoiding heartworm to tackling mites and other harmful parasites, you’re doing a great job as a pet parent by staying informed.

Take those proactive steps today, and if you ever have questions or concerns, reach out to trusted sources like your vet—or visit Supertails for more information on preventive care and a selection of deworming products. 

Your dog’s health journey is a partnership, and together, you can give them the best care possible.